Article
Down-regulation of eukaryotic nitrate transporter by nitrogen-dependent ubiquitinylation.
The Journal of biological chemistry - 12 May 2006
Navarro Francisco J, Machín Félix, Martín Yusé, Siverio José M
Abstract excerpt
In the yeast Hansenula polymorpha, the YNT1 gene encodes the high affinity nitrate transporter, which is repressed by reduced nitrogen sources such as ammonium or glutamine. Ynt1 protein is degraded in response to glutamine in the growth medium. Ynt1 disappears independently of YNT1 glutamine repression as shown in strains where YNT1 repression is abolished. Ynt1-green fluorescent protein chimera and a mutant...
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