Article
Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease.
The Journal of biological chemistry - 4 Aug 2000
Marchal C, Haguenauer-Tsapis R, Urban-Grimal D
Abstract excerpt
Uracil uptake by Saccharomyces cerevisiae is mediated by the FUR4-encoded uracil permease. The modification of uracil permease by phosphorylation at the plasma membrane is a key mechanism for regulating endocytosis of this protein. This modification in turn facilitates its ubiquitination and inte...
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