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Article

Variant estrogen receptor-alpha messenger RNA expression in hormone-independent human breast cancer cells.

Journal of molecular endocrinology - 1 Dec 1999

Coutts A S, Leygue E, Murphy L C

Abstract excerpt

T5-PRF cells are insensitive to the growth-stimulatory effects of estrogen while still retaining expression of estrogen receptor-alpha (ER-alpha). In the apparent absence of ligand, T5-PRF cells have a 3. 6+/-0.5 (s.e.m.)-fold increased basal ER-alpha activity and elevated basal progesterone receptor levels compared with the parent, estrogen-sensitive, T5 cells. Long-range ER-alpha reverse transcription-PCR was...

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Identifiers

PMID: 10601978
DOI: 10.1677/jme.0.0230325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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