Article
Differentially expressed genes and estrogen receptor status in breast cancer.
International journal of oncology - 1 Nov 2003
Nagai Maria Aparecida, Ros Nancy, Bessa Simone Aparecida, Mourão Neto Mário, Miracca Elisabete Cristina, Brentani Maria Mitzi
Abstract excerpt
There is a large and increasing body of experimental and clinical data supporting the involvement of estrogen on the proliferation of hormone-dependent breast tumors. Estrogen acts via its receptor (ER) stimulating cellular proliferation. ER and progesterone receptor (PR), which is regulated by estrogen via ER, have been used as prognostic markers in the clinical management of breast cancer patients. The aim of...
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