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Article

Quantitative profiles of the mRNAs of ER-alpha and its novel variant ER-alpha36 in breast cancers and matched normal tissues.

Journal of Zhejiang University. Science. B - 1 Feb 2010

Zheng Yi, Zhang Jing, Xu Zhen-zhen, Sheng Jian-ming, Zhang Xiao-chen, Wang Hao-hao, Teng Xiao-dong, Liu Xiao-jiao, Cao Jiang, Teng Li-song

Abstract excerpt

OBJECTIVE: The novel estrogen receptor-alpha (ER-alpha) variant ER-alpha36 is reported to be functional in the estrogen signaling pathway and is related to tamoxifen resistance in breast cancer. However, ER-alpha36 tends to be a favorable factor for survival in patients without tamoxifen therapy. To investigate the mechanisms behind this paradox, we determined the differences between the transcriptional profiles...

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Identifiers

PMID: 20104649
DOI: 10.1631/jzus.B0900266
PMCID: PMC2816318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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