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Article

Wild-derived mice: from genetic diversity to variation in immune responses.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2018

Poltorak Alexander, Apalko Svetlana, Sherbak Sergei

Abstract excerpt

Classical inbred mouse strains have historically been instrumental in mapping immunological traits. However, most of the classical strains originate from a relatively limited number of founder animals, largely within the Mus musculus domesticus subspecies. Therefore, their genetic diversity is ultimately limited. For this reason, it is not feasible to use these mice for exhaustive interrogation of immune...

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Identifiers

PMID: 30056578
DOI: 10.1007/s00335-018-9766-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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