Article
Association study of schizophrenia among Indian families.
American journal of medical genetics - 20 Aug 1999
Prasad S, Deshpande S N, Bhatia T, Wood J, Nimgaonkar V L, Thelma B K
Abstract excerpt
A putative association of schizophrenia with a Msc I restriction fragment length polymorphism at the dopamine D3 receptor gene locus (DRD3) was tested among Indian families, using haplotype relative risk analysis and the transmission disequilibrium test (n=66 families and 58 sets of transmissions, respectively). A significant association either with homozygosity or with allele 1 at the biallelic polymporphism...
Topics
- Female
- Genotype
- Homozygote
- Humans
- India
- Linkage Disequilibrium
- Male
- Models, Statistical
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine D2
- Receptors, Dopamine D3
- Schizophrenia
