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Article

Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous-cell carcinoma.

International journal of cancer - 30 Jul 1999

Thomas G R, Chen Z, Oechsli M N, Hendler F J, Van Waes C

Abstract excerpt

We established a new syngeneic murine model of oral squamous-cell carcinoma (SCC) to analyze the potential role of immune recognition determinants in the early development of oral cancer. In this study, we examined whether SCC that undergo transformation and development in the absence of specific immunity exhibit differences in tumorigenicity that relate to differences in expression of CD80, CD86 or MHC class I....

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Source

Identifiers

PMID: 10399955
DOI: 10.1002/(sici)1097-0215(19990730)82:3<377::aid-ijc11>3.0.co;2-9

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