Article
Characterization of the evolution of immune phenotype during the development and progression of squamous cell carcinoma of the head and neck.
Cancer immunology, immunotherapy : CII - 1 Jun 2012
De Costa Anna-Maria A, Schuyler Corinne A, Walker David D, Young M Rita I
Abstract excerpt
While studies have indicated that squamous cell carcinoma of the head and neck (HNSCC) is associated with immune suppression, these studies did not analyze the immune response at the dysplastic stage. The present study utilized a mouse model of 4-nitroquinoline 1-oxide-induced oral carcinogenesis to examine the alterations in immune phenotype at the premalignant and malignant stages of HNSCC. Cervical lymph nodes...
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