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Article

The oxidative stress response mediated via Pos9/Skn7 is negatively regulated by the Ras/PKA pathway in Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Jun 1999

Charizanis C, Juhnke H, Krems B, Entian K D

Abstract excerpt

Exposure of Saccharomyces cerevisiae to elevated concentrations of hydrogen peroxide induces transcription of several genes involved in the oxidative stress response. Two major transcription factors are involved in this induction, Pos9/Skn7 and Yap1. Fusions of either Yap1 or Pos9/Skn7 with the Gal4 DNA binding domain are active as transcription factors. Gal4-Yap1-dependent reporter gene activity is only weakly...

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Source

Identifiers

PMID: 10394911
DOI: 10.1007/s004380050017

Genes

YAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The oxidative stress response mediated via Pos9/Skn7 is negatively regulated by the Ras/PKA pathway in Saccharomyces cerevisiae.PMID 10394911Read ↗

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Yap4 PKA- and GSK3-dependent phosphorylation affects its stability but not its nuclear localization.Semantic proximity Read ↗

The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors.Semantic proximity Read ↗

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