Article
Association of the Skn7 and Yap1 transcription factors in the Saccharomyces cerevisiae oxidative stress response.
Eukaryotic cell - 1 Jun 2011
Mulford K E, Fassler J S
Abstract excerpt
Saccharomyces cerevisiae Skn7p is a stress response transcription factor that undergoes aspartyl phosphorylation by the Sln1p histidine kinase. Aspartyl phosphorylation of Skn7p is required for activation of genes required in response to wall stress, but Skn7p also activates oxidative stress response genes in an aspartyl phosphorylation-independent manner. The presence of binding sites for the Yap1p and Skn7p...
Topics
- DNA-Binding Proteins
- Gene Knockout Techniques
- Genes, Fungal
- Genes, Reporter
- Immunoprecipitation
- Mutation, Missense
- Oxidative Stress
- Peptide Fragments
- Phenotype
- Protein Binding
- Protein Structure, Tertiary
- Response Elements
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcriptional Activation