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Article

Multiple functions of yeast mitochondrial transcription factor Mtf1p during initiation.

The Journal of biological chemistry - 5 Feb 2010

Savkina Maria, Temiakov Dmitry, McAllister William T, Anikin Michael

Abstract excerpt

Transcription of the yeast mitochondrial genome is carried out by an RNA polymerase (Rpo41p) that is related to single subunit bacteriophage RNA polymerases but requires an additional factor (Mtf1p) for initiation. In this work we show that Mtf1p is involved in multiple roles during initiation including discrimination of upstream base pairs in the promoter, initial melting of three to four base pairs around the...

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Identifiers

PMID: 19920143
DOI: 10.1074/jbc.M109.051003
PMCID: PMC2823537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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