Article
Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 1999
O'Shaughnessy K M, Fu B, Ferraro F, Lewis I, Downing S, Morris N H
Abstract excerpt
Preeclampsia is a heritable condition that develops as a result of widespread vascular endothelial dysfunction. The thrombotic tendency in this condition has suggested a number of candidate genes, and there have been recent reports of positive association with the Leiden variant of factor V and the thermolabile variant of methylenetetrahydrofolate reductase. We attempted to reproduce these results in a large...
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