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Article

Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2000

Murphy R P, Donoghue C, Nallen R J, D'Mello M, Regan C, Whitehead A S, Fitzgerald D J

Abstract excerpt

Factor V (FV) Leiden and thermolabile methylenetetrahydrofolate reductase (MTHFR) are 2 common polymorphisms that have been implicated in vascular thrombosis. We determined whether these mutations predicted an adverse outcome in pregnancy. Second, we looked for an interaction between these 2 muta...

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Source

Identifiers

PMID: 10634828
DOI: 10.1161/01.atv.20.1.266

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10634828-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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