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Article

Pronounced phenotype in activated regulatory T cells during a chronic helminth infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2010

Layland Laura E, Mages Jörg, Loddenkemper Christoph, Hoerauf Achim, Wagner Hermann, Lang Roland, da Costa Clarissa U Prazeres

Abstract excerpt

Although several markers have been associated with the characterization of regulatory T cells (Tregs) and their function, no studies have investigated the dynamics of their phenotype during infection. Since the necessity of Tregs to control immunopathology has been demonstrated, we used the chronic helminth infection model Schistosoma mansoni to address the impact on the Treg gene repertoire. Before gene...

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PMID: 20007528
DOI: 10.4049/jimmunol.0901435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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