Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene targeting of retinoid receptors.

Molecular biotechnology - 1 Feb 1999

Lohnes D

Abstract excerpt

Gene targeting in embryonic stem (ES) cells has been employed to investigate the role of the retinoid receptors and binding proteins both in the mouse as well as in embryocarcinoma cells. It is a powerful technique for the modification of the mouse genome. With more recent refinements in gene targeting technology, it is now possible to introduce more subtle mutations in the murine genome, as well as to...

Topics

Animals
Blotting, Southern
Cell Culture Techniques
Cloning, Molecular
DNA
Electroporation
Embryo Implantation
Embryo, Mammalian
Female
Gene Targeting
Genome
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mutation

Receptors, Retinoic Acid

Stem Cells

Source

Identifiers

PMID: 10367283
DOI: 10.1007/BF02789177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene targeting of retinoid receptors.PMID 10367283Read ↗

Gene targeting in the mouse.Semantic proximity Read ↗

Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology.Semantic proximity Read ↗

Gene targeting in ES cells.Semantic proximity Read ↗

Modifying the mouse: design and desire.Semantic proximity Read ↗

Gene disruption in mammals.Semantic proximity Read ↗

Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes.Semantic proximity Read ↗

Overview of gene targeting by homologous recombination.Semantic proximity Read ↗

Using embryonic stem cells to introduce mutations into the mouse germ line.Semantic proximity Read ↗

Mammalian genome targeting using site-specific recombinases.Semantic proximity Read ↗

Gene disruption in mice: models of development and disease.Semantic proximity Read ↗

Inducible gene trapping with drug-selectable markers and Cre/loxP to identify developmentally regulated genes.Semantic proximity Read ↗

Use of transgenic mice to eliminate retinoic acid receptor function in specific tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.