Article
Testing for linkage under robust genetic models.
Human heredity - 1 Jun 1999
Guerra R, Wan Y, Jia A, Amos C I, Cohen J C
Abstract excerpt
Robust genetic models are used to assess linkage between a quantitative trait and genetic variation at a specific locus using allele-sharing data. Little is known about the relative performance of different possible significance tests under these models. Under the robust variance components model approach there are several alternatives: standard Wald and likelihood ratio tests, a quasilikelihood Wald test, and a...
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