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Article

A Recombinant Human Cytomegalovirus with a Large Deletion in <i>UL97</i> Has a Severe Replication Deficiency

1 Jul 1999

Abstract excerpt

Human cytomegalovirus encodes a protein kinase (UL97) that confers sensitivity to ganciclovir by phosphorylating it to the monophosphate. The function of this unusual kinase in viral replication is unknown. We constructed two independent isolates of a recombinant virus, RCDelta97, that contain large deletions in this gene and carry a 4.8-kb insertion containing a selectable genetic marker. These mutant viruses...

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PMID: 10364316
DOI: 10.1128/jvi.73.7.5663-5670.1999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Recombinant Human Cytomegalovirus with a Large Deletion in <i>UL97</i> Has a Severe Replication DeficiencyPMID 10364316Read ↗

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