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Article

Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.

The Journal of general virology - 1 Jun 2001

Marschall Manfred, Stein-Gerlach Matthias, Freitag Martina, Kupfer Regina, van den Bogaard Miriam, Stamminger Thomas

Abstract excerpt

The UL97-encoded protein kinase (pUL97) of human cytomegalovirus (HCMV) plays a critical role in the control of virus replication. Deletion of the UL97 gene results in a drastic reduction in the replication efficiency. Although the exact function of pUL97 remains unclear and its sensitivity to specific inhibitors is speculative, protein kinase inhibitors of the indolocarbazole class are effective inhibitors of...

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PMID: 11369889
DOI: 10.1099/0022-1317-82-6-1439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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