Article
Domain analysis of supervillin, an F-actin bundling plasma membrane protein with functional nuclear localization signals.
Journal of cell science - 1 Jul 1999
Wulfkuhle J D, Donina I E, Stark N H, Pope R K, Pestonjamasp K N, Niswonger M L, Luna E J
Abstract excerpt
A growing number of actin-associated membrane proteins have been implicated in motile processes, adhesive interactions, and signal transduction to the cell nucleus. We report here that supervillin, an F-actin binding protein originally isolated from bovine neutrophil plasma membranes, contains functional nuclear targeting signals and localizes at or near vinculin-containing focal adhesion plaques in COS7-2 and...
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