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Article

Structural basis for the activity of two muconate cycloisomerase variants toward substituted muconates.

Proteins - 1 Jan 1999

Schell U, Helin S, Kajander T, Schlömann M, Goldman A

Abstract excerpt

We have refined to 2.3 A resolution two muconate cycloisomerase (MCIase) variant structures, F329I and I54V, that differ from each other and from wild-type in their activity toward cis,cis-muconate (CCM) and substituted CCMs. The working and free R-factors for F329I are 17.4/21.6% and for I54V, 17.6/22.3% with good stereochemistry. Except for the mutated residue, there are no significant changes in structure. To...

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PMID: 10336378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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