Article
Decreased diversity of hepatitis C virus quasispecies during bone marrow transplantation.
Journal of medical virology - 1 Jun 1999
Ni Y H, Chang M H, Chen P J, Hsu H Y, Lu T W, Lin K H, Lin D T
Abstract excerpt
To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after BMT and the nucleotide diversity and substitution of the hypervariable region (HVR) of HCV...
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