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Article

Carcinogen and dietary lipid regulate ras expression and localization in rat colon without affecting farnesylation kinetics.

Carcinogenesis - 1 May 1999

Davidson L A, Lupton J R, Jiang Y H, Chapkin R S

Abstract excerpt

Epidemiological and experimental data suggest that dietary fiber and fat are major determinants of colorectal cancer. However, the mechanisms by which these dietary constituents alter the incidence of colon cancer have not been elucidated. Evidence indicates that dominant gain-of-function mutations short-circuit protooncogenes and contribute to the pathogenesis of cancer. Therefore, we began to dissect the...

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PMID: 10334194
DOI: 10.1093/carcin/20.5.785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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