Article
Breaking colinearity in the mouse HoxD complex.
Cell - 30 Apr 1999
Kondo T, Duboule D
Abstract excerpt
Vertebrate Hox genes are activated in a spatiotemporal sequence that reflects their clustered organization. While this colinear relationship is a property of most metazoans with an anterior to posterior polarity, the underlying molecular mechanisms are unknown. Previous work suggested that Hox genes were made progressively available for transcription in the course of gastrulation, implying the existence of an...
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