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Article

Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls.

Cell - 28 Jun 1996

van der Hoeven F, Zákány J, Duboule D

Abstract excerpt

Vertebrate Hox genes are activated following a temporal sequence that reflects their linear order in the clusters. We introduced two Hoxd transcription units, labeled with lacZ, to an ectopic 5' position in the HoxD complex. Early expression of the relocated genes was delayed and resembled that of the neighboring Hoxd-13. At later stages, locus-dependent expression in distal limbs and the genital eminence was...

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PMID: 8674109
DOI: 10.1016/s0092-8674(00)81303-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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