Article
Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing.
Proceedings of the National Academy of Sciences of the United States of America - 11 May 1999
Chen H R, Tsao T Y, Chen C H, Tsai W Y, Her L S, Hsu M M, Cheng S C
Abstract excerpt
The SNT309 gene was identified via a mutation that causes lethality of cells in combination with a prp19 mutation. We showed previously that Snt309p is a component of the Prp19p-associated complex and that Snt309p, like Prp19p, is associated with the spliceosome immediately after or concomitantly with dissociation of U4 from the spliceosome. We show here that extracts prepared from the SNT309-deleted strain...
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