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Article

The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993

Arenas J E, Abelson J N

Abstract excerpt

In Saccharomyces cerevisiae, the prp21 mutation causes accumulation of unspliced pre-mRNA at the nonpermissive temperature. We have cloned the PRP21 gene by complementation of its temperature-sensitive phenotype and found it to be the same as SPP91, an extragenic suppressor of the prp9 mutation previously studied in vivo by Chapon and Legrain [Chapon, C. & Legrain, P. (1992) EMBO J. 11, 3279-3288]. We have...

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Identifiers

PMID: 8341697
DOI: 10.1073/pnas.90.14.6771
PMCID: PMC47014

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Source receipt: pubmed, retrieved 7 Sept 2026.

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