Article
The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993
Arenas J E, Abelson J N
Abstract excerpt
In Saccharomyces cerevisiae, the prp21 mutation causes accumulation of unspliced pre-mRNA at the nonpermissive temperature. We have cloned the PRP21 gene by complementation of its temperature-sensitive phenotype and found it to be the same as SPP91, an extragenic suppressor of the prp9 mutation p...
Topics
- Cloning, Molecular
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- RNA Precursors
- RNA Splicing
- RNA, Small Nuclear
- RNA-Binding Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Spliceosomes