Article
Bioavailability of tramadol after i.m. injection in comparison to i.v. infusion.
International journal of clinical pharmacology and therapeutics - 1 Apr 1999
Lintz W, Beier H, Gerloff J
Abstract excerpt
OBJECTIVES AND METHODS: The bioavailability of tramadol after i.m. injection of tramadol-HCl was determined from serum concentration data in a balanced two-period crossover study with 12 healthy male subjects in comparison to the 30-min i.v. infusion. Additionally, the tramadol concentrations in saliva and urine samples were measured. The subjects received single doses of 50 mg after an overnight fast, the...
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