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Article

Pharmacokinetics of tramadol and its three main metabolites in healthy male and female volunteers.

Biopharmaceutics & drug disposition - 1 Dec 2007

Ardakani Yalda H, Rouini Mohammad-Reza

Abstract excerpt

By using a high-performance liquid chromatography method, the pharmacokinetics of the tramadol (T) and its three main metabolites, O-desmethyltramadol (M1), N-desmethyltramadol (M2) and O,N-didesmethyltramadol (M5) was studied in healthy male and female Iranian volunteers after oral administratio...

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Identifiers

PMID: 17891748
DOI: 10.1002/bdd.584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17891748-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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