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Article

Human retinoic X receptor beta: complete genomic sequence and mutation search for ossification of posterior longitudinal ligament of the spine.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1999

Numasawa T, Koga H, Ueyama K, Maeda S, Sakou T, Harata S, Leppert M, Inoue I

Abstract excerpt

Ossification of the posterior longitudinal ligament of the spine (OPLL) is characterized by ectopic bone formation in the ligament. OPLL is a very common disorder, in fact it constitutes the leading cause of myelopathy among Japanese. In the previous report, we provided the genetic linkage evidence that the genetic susceptibility of OPLL mapped to HLA complex of chromosome 6. As a candidate gene approach,...

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Identifiers

PMID: 10234570
DOI: 10.1359/jbmr.1999.14.4.500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human retinoic X receptor beta: complete genomic sequence and mutation search for ossification of posterior longitudinal ligament of the spine.PMID 10234570Read ↗

Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

Genetic mapping of ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

Recent progress in the study of pathogenesis of ossification of the posterior longitudinal ligament.Semantic proximity Read ↗

TGFBR2 gene polymorphism is associated with ossification of the posterior longitudinal ligament.Semantic proximity Read ↗

[Updates on ossification of posterior longitudinal ligament. Genetic approach to the susceptibility genes for ossification of posterior longitudinal ligament of the spine (OPLL) and for its molecular pathogenesis].Semantic proximity Read ↗

Association between single nucleotide polymorphism of IL15RA gene with susceptibility to ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

[Genomic analysis of ossification of the posterior longitudinal ligament].Semantic proximity Read ↗

Association between interleukin 15 receptor, alpha (IL15RA) polymorphism and Korean patients with ossification of the posterior longitudinal ligament.Semantic proximity Read ↗

Restriction fragment length polymorphism of genes of the alpha 2(XI) collagen, bone morphogenetic protein-2, alkaline phosphatase, and tumor necrosis factor-alpha among patients with ossification of posterior longitudinal ligament and controls from the Japanese population.Semantic proximity Read ↗

A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

A single nucleotide polymorphism in the human bone morphogenetic protein-2 gene (109T > G) affects the Smad signaling pathway and the predisposition to ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read ↗

COL6A1, the candidate gene for ossification of the posterior longitudinal ligament, is associated with diffuse idiopathic skeletal hyperostosis in Japanese.Semantic proximity Read ↗

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