Article
Recent progress in the study of pathogenesis of ossification of the posterior longitudinal ligament.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association - 1 Jan 2000
Sakou T, Matsunaga S, Koga H
Abstract excerpt
The pathogenesis of ossification of the posterior longitudinal ligament (OPLL) is still unknown. Gene analysis and molecular biology have been introduced in recent years, and etiologic and pathological clarifications are being achieved. An important role of the genetic background in the development of this disease was demonstrated by pedigree survey, twin survey, and HLA haplotype study. The results of gene...
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