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Article

Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing.

Genetics - 1 Jul 2003

Vincent Kevin, Wang Qiang, Jay Steven, Hobbs Kathryn, Rymond Brian C

Abstract excerpt

Clf1 is a conserved spliceosome assembly factor composed predominately of TPR repeats. Here we show that the TPR elements are not functionally equivalent, with the amino terminus of Clf1 being especially sensitive to change. Deletion and add-back experiments reveal that the splicing defect associ...

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Identifiers

PMID: 12871902
DOI: 10.1093/genetics/164.3.895
PMCID: PMC1462608

Genes

TPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12871902-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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