Article
Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population.
FEBS letters - 1 Apr 1999
Oscarson M, McLellan R A, Gullstén H, Yue Q Y, Lang M A, Bernal M L, Sinues B, Hirvonen A, Raunio H, Pelkonen O, Ingelman-Sundberg M
Abstract excerpt
Cytochrome P450 2A6 is an important human hepatic P450 which activates pre-carcinogens, oxidises some drugs and constitutes the major nicotine C-oxidase. In fact, results have been presented in the literature which suggested a relationship between the distribution of defective CYP2A6 alleles and...
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