Article
Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase.
FEBS letters - 6 Nov 1998
Oscarson M, Gullstén H, Rautio A, Bernal M L, Sinues B, Dahl M L, Stengård J H, Pelkonen O, Raunio H, Ingelman-Sundberg M
Abstract excerpt
Cytochrome P450 2A6 (CYP2A6) is a polymorphic enzyme responsible for the oxidation of certain precarcinogens and drugs and is the major nicotine C-oxidase. The role of CYP2A6 for nicotine elimination was emphasised recently by the finding that smokers carrying defective CYP2A6 alleles consumed fe...
Topics
- Aryl Hydrocarbon Hydroxylases
- Cytochrome P-450 CYP2A6
- Cytochrome P-450 Enzyme System
- Diabetes Mellitus, Type 2
- Ethnicity
- Finland
- Genotype
- Humans
- Mixed Function Oxygenases
- Oxidoreductases
- Phenotype
- Polymerase Chain Reaction
- Smoking
- Spain
- Sweden
- Tobacco Use Disorder
- White People