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Article

A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity.

Human mutation - 1 Mar 2004

Pitarque Marià, von Richter Oliver, Rodríguez-Antona Cristina, Wang Jue, Oscarson Mikael, Ingelman-Sundberg Magnus

Abstract excerpt

In humans, several polymorphic variants have been described for the gene encoding the major nicotine C-oxidase, cytochrome P450 2A6 (CYP2A6), which is to a great extent responsible for the large interindividual differences seen at the enzymatic and activity levels. Hitherto, mainly polymorphic variants in the open reading frame have been identified. In the present study, we identified a novel single nucleotide...

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PMID: 14974084
DOI: 10.1002/humu.20002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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