Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic linkage of beta and gamma subunits of epithelial sodium channel to systolic blood pressure.

Lancet (London, England) - 10 Apr 1999

Wong Z Y, Stebbing M, Ellis J A, Lamantia A, Harrap S B

Abstract excerpt

BACKGROUND: Mutations in the genes on chromosome 16p12 that encode the beta and gamma subunits of the epithelial sodium channel (SCNNIB and SCNNIG, respectively) have been linked with rare sodium-dependent forms of low and high blood pressure. Other DNA variants in or around these genes may contribute to variation in blood pressure and the risk of coronary heart disease and stroke. METHODS: We studied 286 white...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Body Mass Index
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family

Share to Least-Squares Analysis

Share to Sodium Channels

Share to Statistics, Nonparametric

Share to Victoria

Source

Identifiers

PMID: 10217082
DOI: 10.1016/S0140-6736(98)10118-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic linkage of beta and gamma subunits of epithelial sodium channel to systolic blood pressure.PMID 10217082Read ↗

Selective genotyping reveals association between the epithelial sodium channel gamma-subunit and systolic blood pressure.Semantic proximity Read ↗

The epithelial sodium channel γ-subunit gene and blood pressure: family based association, renal gene expression, and physiological analyses.Semantic proximity Read ↗

Genome-wide scan for blood pressure in Australian and Dutch subjects suggests linkage at 5P, 14Q, and 17P.Semantic proximity Read ↗

Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings.Semantic proximity Read ↗

Rare Variants in Genes Encoding Subunits of the Epithelial Na+ Channel Are Associated With Blood Pressure and Kidney Function.Semantic proximity Read ↗

Associations of epithelial sodium channel genes with blood pressure: the GenSalt study.Semantic proximity Read ↗

SacI identifies a biallelic polymorphism in the coding sequence of the gamma subunit of the epithelial sodium channel (ENaC): a candidate gene for hypertension.Semantic proximity Read ↗

Heritability and Genetic Linkage of Plasma Natriuretic Peptide LevelsSemantic proximity Read ↗

Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study.Semantic proximity Read ↗

Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure.Semantic proximity Read ↗

Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs.Semantic proximity Read ↗

Common variants in epithelial sodium channel genes contribute to salt sensitivity of blood pressure: The GenSalt study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.