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Article

Regulation of partitioned sterol biosynthesis in Saccharomyces cerevisiae.

Journal of bacteriology - 1 Nov 1992

Casey W M, Keesler G A, Parks L W

Abstract excerpt

Using yeast strains with null mutations in structural genes which encode delta-aminolevulinic acid synthetase (HEM1), isozymes of 3-hydroxy-3-methylglutaryl coenzyme A (HMG1 and HMG2), squalene epoxidase (ERG1), and fatty acid delta 9-desaturase (OLE1), we were able to determine the effect of hemes, sterols, and unsaturated fatty acids on both sterol production and the specific activity of...

Topics

5-Aminolevulinate Synthetase
Ergosterol
Fatty Acid Desaturases
Fatty Acids
Genes, Fungal
Genotype
Hydroxymethylglutaryl CoA Reductases
Isoenzymes
Kinetics
Mevalonic Acid
Mutagenesis
Oleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oleic Acids

Oxygenases

Saccharomyces cerevisiae

Squalene Monooxygenase

Sterols

Source

Open in PubMed Open full text

Identifiers

PMID: 1429452
DOI: 10.1128/jb.174.22.7283-7288.1992
PMCID: PMC207422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1429452-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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