Article
Regulation of partitioned sterol biosynthesis in Saccharomyces cerevisiae.
Journal of bacteriology - 1 Nov 1992
Casey W M, Keesler G A, Parks L W
Abstract excerpt
Using yeast strains with null mutations in structural genes which encode delta-aminolevulinic acid synthetase (HEM1), isozymes of 3-hydroxy-3-methylglutaryl coenzyme A (HMG1 and HMG2), squalene epoxidase (ERG1), and fatty acid delta 9-desaturase (OLE1), we were able to determine the effect of hemes, sterols, and unsaturated fatty acids on both sterol production and the specific activity of...
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