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Article

Repression of hepatitis B virus X gene expression by hammerhead ribozymes.

Biochemical and biophysical research communications - 21 Apr 1999

Kim Y K, Junn E, Park I, Lee Y, Kang C, Ahn J K

Abstract excerpt

The X protein (HBx) of human hepatitis B virus (HBV) is a transcriptional activator protein. The HBx protein plays an important role in viral replication in HBV infected cells and the liver diseases including hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Therefore, the repression of HBx gene expression by hammerhead ribozymes may be a good way to inhibit HBV replication and cure HBV-related liver...

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Identifiers

PMID: 10208856
DOI: 10.1006/bbrc.1999.0537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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