Article
Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site.
The Journal of biological chemistry - 23 Apr 1999
Amendt B A, Sutherland L B, Russo A F
Abstract excerpt
The recently described Hmx family of homeodomain proteins is predominately expressed in discrete regions of developing sensory tissues. In this report, we have identified the preferred DNA-binding site of the murine Hmx3 homeodomain protein by the selection and amplification binding (SAAB) technique. The consensus Hmx-binding site contained the sequence 5'-CAAGTG-3', which differs from the 5'-TAAT-3' motif...
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