Article
Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia.
Arquivos de neuro-psiquiatria - 1 Mar 2007
Bertola Vivian, Cordeiro Quirino, Zung Stevin, Miracca Elisabete Cristina, Vallada Homero
Abstract excerpt
Data from epidemiological studies have demonstrated that genetics is an important risk factor for schizophrenia. Disturbances of serotonergic brain pathways have been implicated in the pathophysiology of schizophrenia. Some studies have suggested that the efficacy of atypical antipsychotics on schizophrenia treatment may be related to the serotonin 2A receptor (5-HT2A), and that serotonergic drugs may induce...
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