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Article

Sjögren's syndrome: lymphoma predisposition coupled with a reduced frequency of t(14;18) translocations in blood lymphocytes.

Molecular carcinogenesis - 1 Mar 1999

Henriksson G, Brant M, Sandor Z, Manthorpe R, Bredberg A

Abstract excerpt

Sjögren's syndrome (SS) is a systemic autoimmune disorder with a strong tumor predisposition (a 44-fold elevated incidence of non-Hodgkin's lymphoma has been reported). By polymerase chain reaction analysis of t(14;18), a key lymphomagenic event in peripheral blood lymphocytes, we found a lower frequency in a subset of 12 SS patients positive for SS-A/SS-B autoantibodies than in 21 healthy subjects and 20 SS...

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Share to Antibodies, Antinuclear
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 18

Share to DNA Nucleotidyltransferases

Share to Genes, bcl-2

Share to Lymphoma, Non-Hodgkin

Share to Sjogren's Syndrome

Share to VDJ Recombinases

Source

Identifiers

PMID: 10204807
DOI: 10.1002/(sici)1098-2744(199903)24:3<226::aid-mc9>3.0.co;2-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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