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Article

High frequency of t(14;18) translocation in salivary gland lymphomas from Sjögren's syndrome patients.

1 Nov 1991

Abstract excerpt

Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by lymphocytic infiltration of the salivary and lacrimal glands. These patients have a markedly increased frequency of developing non-Hodgkin's lymphoma in their salivary glands and cervical lymph nodes. Translocations of proto-oncogene bcl-2 t(14;18) were observed in five of seven SS-associated lymphomas by Southern blot analysis. Using...

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Share to Glycosylation and Glycoproteins Research
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PMID: 1940802
DOI: 10.1084/jem.174.5.1245

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