Article
Linkage analysis of glucocorticoid and beta2-adrenergic receptor genes with blood pressure and body mass index.
The American journal of physiology - 1 Apr 1999
Takami S, Wong Z Y, Stebbing M, Harrap S B
Abstract excerpt
Glucocorticoids and catecholamines exert important effects on cardiovascular physiology and metabolism. Variants of the glucocorticoid receptor gene (GRL) and the beta2-adrenergic receptor gene (ADRB2) have been associated with high blood pressure and obesity. These genes are close on human chromosome 5q31-5q32, and we undertook a linkage analysis of this region in 264 families from the general population in...
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