Article
Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation.
Human molecular genetics - 1 Sept 1998
Krushkal J, Xiong M, Ferrell R, Sing C F, Turner S T, Boerwinkle E
Abstract excerpt
Elevated blood pressure is an important risk factor for renal-, cerebro- and cardiovascular diseases. We used an efficient discordant sib-pair ascertainment scheme to investigate the impact of the distal end of the long arm of human chromosome 5 (chromosomal region 5q31.1-qter) containing genes f...
Topics
- Adolescent
- Adult
- Blood Pressure
- Child
- Chromosomes, Human, Pair 5
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Humans
- Male
- Pedigree
- Polymorphism, Genetic
- Receptors, Adrenergic
- Receptors, Adrenergic, alpha-1
- Receptors, Adrenergic, beta-2
- Receptors, Dopamine D1
- Risk Factors