Article
An affected pedigree member analysis of linkage between the dopamine D2 receptor gene TaqI polymorphism and obesity and hypertension.
International journal of cardiology - 22 Jun 2005
Fang Yu-Jing, Thomas G Neil, Xu Zong-Li, Fang Ji-Qian, Critchley Julian A J H, Tomlinson Brian
Abstract excerpt
BACKGROUND: Dopamine modulates a variety of physiological functions including natriuresis and satiety. We have previously reported that the TaqI polymorphism of the dopamine D2 receptor (DD2R) gene is associated with both blood pressure and obesity indices in a normoglycaemic Hong Kong Chinese population. In this study, we present evidence confirming the linkage between this gene polymorphism, obesity and...
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