Article
SGD1 encodes an essential nuclear protein of Saccharomyces cerevisiae that affects expression of the GPD1 gene for glycerol 3-phosphate dehydrogenase.
FEBS letters - 20 Oct 2000
Akhtar N, Påhlman A K, Larsson K, Corbett A H, Adler L
Abstract excerpt
We here report the identification of the previously uncharacterized SGD1 gene, encoding a 102.8-kDa protein containing a leucine zipper region and a bipartite nuclear localization signal. Deletion of SGD1 results in loss of cell viability, while an increased dosage of SGD1 partially suppresses th...
Topics
- Cell Division
- Cloning, Molecular
- Fluorescent Antibody Technique, Indirect
- Gene Deletion
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Genes, Essential
- Glycerol
- Glycerolphosphate Dehydrogenase
- Green Fluorescent Proteins
- Luminescent Proteins
- Microscopy, Fluorescence
- Mutation
- Nuclear Proteins