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Article

Intracellular glycerol levels modulate the activity of Sln1p, a Saccharomyces cerevisiae two-component regulator.

The Journal of biological chemistry - 1 Jan 1999

Tao W, Deschenes R J, Fassler J S

Abstract excerpt

The HOG mitogen-activated protein kinase pathway mediates the osmotic stress response in Saccharomyces cerevisiae, activating genes like GPD1 (glycerol phosphate dehydrogenase), required for survival under hyperosmotic conditions. Activity of this pathway is regulated by Sln1p, a homolog of the "two-component" histidine kinase family of signal transduction molecules prominent in bacteria. Sln1p also regulates the...

Topics

Base Sequence
Cloning, Molecular
DNA Primers
Fungal Proteins
Genetic Complementation Test
Glycerol
Intracellular Signaling Peptides and Proteins
Lac Operon
Membrane Proteins
Mutation
Osmosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Kinases

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9867851
DOI: 10.1074/jbc.274.1.360
PMCID: PMC2909977

Genes

GPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9867851-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Intracellular glycerol levels modulate the activity of Sln1p, a Saccharomyces cerevisiae two-component regulator.PMID 9867851Read ↗

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