Initiation of the transcriptional response to hyperosmotic shock correlates with the potential for volume recovery.

doi:10.1111/febs.12382

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Article

Initiation of the transcriptional response to hyperosmotic shock correlates with the potential for volume recovery.

The FEBS journal - 1 Aug 2013

Geijer Cecilia, Medrala-Klein Dagmara, Petelenz-Kurdziel Elzbieta, Ericsson Abraham, Smedh Maria, Andersson Mikael, Goksör Mattias, Nadal-Ribelles Mariona, Posas Francesc, Krantz Marcus, Nordlander Bodil, Hohmann Stefan

Abstract excerpt

The control of activity and localization of transcription factors is critical for appropriate transcriptional responses. In eukaryotes, signal transduction components such as mitogen-activated protein kinase (MAPK) shuttle into the nucleus to activate transcription. It is not known in detail how different amounts of nuclear MAPK over time affect the transcriptional response. In the present study, we aimed to...

Topics

Adaptation, Physiological
Cell Nucleus
Glycerol
Glycerol-3-Phosphate Dehydrogenase (NAD+)
Hypertonic Solutions
Indicators and Reagents
Kinetics
MAP Kinase Signaling System
Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Osmotic Pressure

Phosphorylation

Promoter Regions, Genetic

Protein Processing, Post-Translational

Protein Transport

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Stress, Physiological

Source

Open in PubMed

Identifiers

PMID: 23758973
DOI: 10.1111/febs.12382

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23758973-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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