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Article

Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification.

Neuron - 1 Mar 1999

Lu T, Nguyen B, Zhang X, Yang J

Abstract excerpt

Inwardly rectifying K+ channels bind intracellular magnesium and polyamines to generate inward rectification. We have examined the architecture of the inner pore of Kir2.1 channels by covalently attaching a constrained number (from one to four) of positively charged moieties of different sizes to...

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Identifiers

PMID: 10197536
DOI: 10.1016/s0896-6273(00)80711-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10197536-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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