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Article

Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1.

The Journal of general physiology - 1 Apr 1999

Lee J K, John S A, Weiss J N

Abstract excerpt

Inward rectifying K channels are essential for maintaining resting membrane potential and regulating excitability in many cell types. Previous studies have attributed the rectification properties of strong inward rectifiers such as Kir2.1 to voltage-dependent binding of intracellular polyamines o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10102936
DOI: 10.1085/jgp.113.4.555
PMCID: PMC2217169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10102936-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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